Chemical Synthesis and In Vitro Antitumor Activity of Quinizarin Glycoside Analogs |
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| Authors: | Xiaofei Sun Li Ji Sumei Ren Shengbiao Wan |
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| Affiliation: | School of Medicine and Pharmacy, Key Laboratory of Marine Drugs, Ministry of Education , Ocean University of China , Qingdao, China |
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| Abstract: | A series of new glycoside derivatives of quinizarin were synthesized and characterized by NMR and IR spectrometry, and in vitro antitumor activity of some of these derivatives was evaluated against the mouse leukaemia P388 and the human leukaemia HL-60 cell lines by the standard MTT assay. They were proven to possess moderate antitumor activity. |
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| Keywords: | Antitumor activity chemical synthesis glycoside derivatives quinizarin |
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