P4VP-H2SO4-Catalyzed Chemoselective Protection of Aldehydes to Acylal Along with Deprotection Reactions |
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| Authors: | Papia Dutta Parishmita Sarma |
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| Affiliation: | Department of Chemical Sciences , Tezpur University , Napaam , Tezpur-Assam , India |
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| Abstract: | Poly(4-vinylpyridine)-supported sulfuric acid is an excellent reusable heterogeneous catalyst for the chemoselective synthesis of 1,1-diacetates(acylal) from aldehydes in dichloromethane at room temperature within a few minutes. The protection of salicyaldehyde generated an anhydro-dimer as single product under similar reaction conditions. The catalyst is equally applicable for the deprotection of acylal in acetonitrile. The catalyst was prepared by the wet impregnation technique. |
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| Keywords: | Chemoselectivity 1,1-diacetates protection–deprotection reusable catalyst supported solid acid |
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