A Convenient Synthesis of Cholest-2-En-6-ONE |
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| Authors: | Elliott B. Byall F. Thomas Bond |
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| Affiliation: | 1. Department of Chemistry , Oregon State University , Corvallis, Oregon, 97331;2. Department of Chemistry , University of California , San Diego Box 109, La Jolla, California, 92037 |
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| Abstract: | Cholest-2-on-6-one, 3, is an important synthetic intermediate in the preparation of ecdysone and related insect moulting hormones.1–3 We report here a convenient two-step synthesis of this compound from cholesterol which combines in one step the elimination of a 36 borate ester and hydroboration-oxidation at C-6. |
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