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Solvent-free microwave-assisted synthesis of imidazo[1,5- a]pyridine and –quinoline derivatives |
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| Authors: | Jasmin Martha Herr Carina Rössiger Georg Albrecht Hisao Yanagi |
| Institution: | 1. Institute of Organic Chemistry, Justus-Liebig-University Giessen, Giessen, Germany;2. Center for Materials Research (LaMa), Justus-Liebig-University Giessen, Giessen, Germany;3. Institute of Applied Physics, Justus-Liebig-University Giessen, Giessen, Germany;4. Department of Materials Science, NAIST, Nara, Japan |
| Abstract: | A quick and highly efficient microwave-assisted preparation of imidazopyridines and –quinolines is described, starting from the corresponding ketones and amines. The method requires no solvent and uses activated MnO2 as an oxidant. A mechanism for the cyclization is proposed and discussed. |
| Keywords: | Condensation reaction microwave reaction MnO2 imidazo[1 5-a]pyridine rearrangement |