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Novel Iodine Reagent System for Regioselective Cleavage of Epoxides to Alcohols
Authors:Vikas N Telvekar  Rajesh A Rane
Institution:1. Department of Pharmaceutical Sciences and Technology , University Institute of Chemical Technology , Matunga, Mumbai, India vikastelvekar@rediffmail.com;3. Department of Pharmaceutical Sciences and Technology , University Institute of Chemical Technology , Matunga, Mumbai, India
Abstract:Epoxides are converted regioselectively to corresponding higher substituted alcohols with greater yields using diphosphorus tetraiodide (P2I4) as a reducing agent and a catalytic amount of tetraethylammonium bromide at room temperature.
Keywords:Alcohols  diphosphorus tetraiodide  epoxides  reduction  tetraethylammonium bromide
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