An Improved Procedure for the Synthesis of Ethyl Glycidate |
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Authors: | Hassan Y. Aboul-enein |
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Affiliation: | The Toxicology Center, Department of Pharmacology , College of Medicine, The University of Iowa , Iowa City, Iowa, 52242 |
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Abstract: | Ethylglycidate (1), is a useful intermediate which can be used in several reactions involving epoxide ring opening with the introduction of an ester function and in co-polymer chemistry (1,2). Emmons and Pagano (3) described the preparation of I by epoxidation of ethyl acrylate with peroxytrifluoroacetic acid in 54% yield. |
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