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An Improved Procedure for the Synthesis of Ethyl Glycidate
Authors:Hassan Y. Aboul-enein
Affiliation:The Toxicology Center, Department of Pharmacology , College of Medicine, The University of Iowa , Iowa City, Iowa, 52242
Abstract:Ethylglycidate (1), is a useful intermediate which can be used in several reactions involving epoxide ring opening with the introduction of an ester function and in co-polymer chemistry (1,2). Emmons and Pagano (3) described the preparation of I by epoxidation of ethyl acrylate with peroxytrifluoroacetic acid in 54% yield.
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