Synthesis,Structural, and Physicochemical Study of First- and Second-Generation Melamine-Based Dendrimers

Abstract

First-tier (G₁) 2,4,6-tridiethymalonate-triazine (2,4,6-TDEMTA) and second-tier (G₂) 2,4,6-hexadiethylmalonate-triazine (2,4,6-HDEMTA) dendrimers were prepared with melamine (1,3,5-triazine) as core (G₀) and sodium malonate ester for bifurcation of chains. The trichlorotriazine (TCT) and sodium diethyl malonate (SDEM) aqueous solutions were mixed, and a creamy white precipitate of G₁ was obtained. The G₁ was hydrolyzed in alkaline medium to prepare 2,4,6-tridisodiummalonate-triazine (2,4,6-TDSMTA) by replacing ?C₂H₅ groups of COOC₂H₅ by Na, which was further neutralized by dilute HCl to obtain 2,4,6-trimalonicacid-triazine (2,4,6-TMATA). The TMATA was treated with PCl₅(s) to form –COCl, which was treated with SDEM to form the G₂.