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Asymmetric Addition of Diethylzinc to Ketones promoted by Tartaric Acid Derivatives |
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| Authors: | Ailing Hui Jintang Zhang |
| Institution: | 1. Engineering Research Center of Bio-process, Hefei University of Techonology, Ministry of Education , Hefei, China;2. Department of Chemistry , University of Science and Technology of China , Hefei, China |
| Abstract: | The preparation of new sulfonamide ligands derived from L-tartaric acid and camphor sulfonyl chloride are described. The employment in the titanium tetraisopropoxide-promoted enantioselective addition of diethylzinc to ketones has been studied. The best enantiomeric excess is up to 99% with 7 mol% catalyst loading at room temperature. |
| Keywords: | Asymmetric addition Diethylzinc Ketone Sulfonamide Tartaric acid |