Efficient and Novel Synthesis of Benzoxazole Derivatives in the Presence of Zinc Dust Under Solvent-Free Conditions |
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| Authors: | M. S. R. Murty Kesur R. Ram Rayudu Venkateswara Rao J. S. Yadav |
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| Affiliation: | 1. Organic Chemistry Division I , Indian Institute of Chemical Technology , Hyderabad, India msrmurty@ymail.com;3. Organic Chemistry Division I , Indian Institute of Chemical Technology , Hyderabad, India |
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| Abstract: | A mild and efficient method has been developed for the synthesis of 2-cyclic amine-substituted benzoxazole derivatives using zinc dust under microwave irradiation in the absence of solvent is described. A comparative study was performed under conventional and microwave heating conditions. Zinc dust can be reused several times after reactivation. The significant feature of this method is the isolation of the pure product by simple workup in a short reaction time with high purity. |
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| Keywords: | Benzoxazole cyclic amine microwave solvent free zinc dust |
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