ZnO Nanoparticles: A Mild and Efficient Reusable Catalyst for the One-Pot Synthesis of 4-Amino-5-pyrimidinecarbonitriles Under Aqueous Conditions |
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| Authors: | Rahim Hekmatshoar Ghodsieh Nanva Kenary Sodeh Sadjadi Yahya S. Beheshtiha |
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| Affiliation: | 1. Department of Chemistry , School of Science, Alzahra University , Vanak, Tehran, Iran rhekmatus@yahoo.com;3. Department of Chemistry , School of Science, Alzahra University , Vanak, Tehran, Iran |
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| Abstract: | An efficient method for the synthesis of 4-amino-5-pyrimidinecarbonitriles by three-component reaction of malononitrile, aldehydes, and N-unsubstituted amidines, under aqueous conditions, using ZnO nanoparticles as catalyst is reported. The catalyst exhibited remarkable activity and is recyclable. |
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| Keywords: | Aldehydes amidines 4-amino-5-pyrimidinecarbonitriles malononitrile ZnO nanoparticles |
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