Easy Access to cis-3-(Benzoxazol-2-yl)cyclopentanecarboxylic Acids from Camphorquinone and o-Aminophenols via an Unexpected Opening of Camphor Ring |
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Authors: | Joanna Nowicka-Scheibe |
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Institution: | 1. West Pomeranian University of Technology , Szczecin, Institute of Chemistry and Environmental Protection , Szczecin , Poland joannans@zut.edu.pl |
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Abstract: | An unexpected formation of cis-1,2,2-trimethyl-3-(benzoxazol-2-yl)cyclopenta-necarboxylic acids was observed as the result of an oxidative C-C bond cleavage of the camphor ring in the intermediate imine during the condensation reactions between camphoroquinone and o-aminophenols conducted under open air conditions. Supplemental materials are available for this article. Go to the publisher's online edition of Synthetic Communications® to view the free supplemental file. |
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Keywords: | Air oxidation benzoxazole caphoroquinone condensation o-aminophenols ring opening |
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