An Efficient Method for N-Nitrosation of Secondary Amines Under Mild and Heterogeneous Conditions |
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| Authors: | Mohammad Ali Zolfigol Ezat Ghaemi Elahe Madrakian Maryam Kiany-Borazjani |
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| Institution: | Chemistry Department , College of Science, Bu-Ali Sina University , Hamadan , 65174 , Iran E-mail: Zolfi@basu.ac.ir |
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| Abstract: | A combination of inorganic acidic salts or silica gel supported inorganic acids and sodium nitrite in the presence of wet SiO2 was used as an effective nitrosating agent for the nitrosation of secondary amines to their corresponding nitroso drivatives under mild and heterogeneous conditions in moderate to excellent yields. Mg(HSO4)2 and NaHSO4 are superior to all the aforementioned reagents in convenience, yield and purity of the isolated nitrosoamines. |
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