Water-Mediated Synthesis of Benzazole and Thiourea Motifs by Reacting Naturally Occurring Isothiocyanate with Amines |
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| Authors: | Ritika Sharma Manju Bala Praveen Kumar Verma |
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| Institution: | 1. Natural Product Chemistry and Process Development Division, CSIR Institute of Himalayan Bioresource Technology, Palampur, Himachal Pradesh, India;2. Academy of Scientific and Innovative Research, New Delhi, India |
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| Abstract: | An efficient, green, and facile method has been developed for the synthesis of benzazole and thiourea analogues from naturally occurring erucin in moderate to good yields. The reaction was carried out in water without using any metal catalyst or base. The present method tolerated the various functional groups on aromatic rings and also applicable for other isothiocyanates. |
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| Keywords: | Benzazoles erucin isothiocyanates thiourea water-mediated synthesis |
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