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Synthesis of New Water-Soluble Cholesterol Derivatives
Authors:Florian Schmidt  Michael Spoerner  Hans Robert Kalbitzer
Affiliation:1. Institute for Organic Chemistry, University of Regensburg , Regensburg , Germany;2. Institute for Biophysics and Physical Biochemistry, University of Regensburg , Regensburg , Germany
Abstract:L-Proline has been used as an organocatalyst for an efficient synthesis of 1,8-dioxo-octahydroxanthenes by treatment of aldehydes (aromatic, heteroaromatic, and aliphatic) with 5,5-dimethyl-1,3-cyclohexanedione. Three new compounds have been prepared.
Keywords:Cholesterol  ethylene glycol  reductive amination  steroid  water-soluble
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