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Novel Synthesis of Isoquinoline Derivatives Derived from (Z)-4-(1,3-Diphenylpyrazol-4-yl)isochromene-1,3-dione
Authors:Mahmoud R. Mahmoud  Manal M. El-Shahawi  Mohamed H. Hekal
Affiliation:Chemistry Department, Faculty of Science, Ain Shams University, Cairo, Egypt
Abstract:A series of isoquinoline derivatives were synthesized via the reaction of the (Z)-4-(1,3-diphenylpyrazol-4-yl)isochromene-1,3-dione with different hydrazides, primary amines, diamines, 2-aminothiophenol, 2-aminobenzoic acid, p-aminoacetophenone, and ethyl 2-amino-4,5,6,7-tetrahydrobenzo-[b]thiophene-3-carboxylate. All the synthesized compounds were characterized by infrared, 1H NMR, and mass spectra besides the analytical data.
Keywords:Fused heterocycles  isochromene-1,3-dione  isoquinoline
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