Microwave-Assisted Michael Addition of Diethyl Malonate with Ferrocenyl Substituted Chalcones Under Solvent-Free Conditions |
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| Authors: | Zhi-Liang Shen Da-Gong Gu Jin-Ming Yang |
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| Institution: | 1. Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science , Suzhou (Soochow) University , Suzhou , People's Republic of China;2. Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science , Suzhou (Soochow) University , Suzhou , People's Republic of China;3. Key Laboratory of Coastal Wetland Bioresources and Environmental Protection of Jiangsu Province, College of Chemistry and Chemical Engineering , Yancheng Teachers University , Yancheng , People's Republic of China |
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| Abstract: | The article describes an efficient, economical, and environmentally friendly approach for Michael addition of diethyl malonate to ferrocenyl substituted chalcones in the presence of microwave irradiation under solvent-free conditions, affording the corresponding Michael adducts in moderate to good yields of 53–94%.  Additional information ACKNOWLEDGMENTS This work was partially supported by the Key Laboratory of Organic Synthesis of Jiangsu Province at Suzhou University (No. S8109108), the Natural Science Foundation of Jiangsu Province (No. BK2006048), the National Science Foundation of China (Nos. 20472062, 20672079), the Nature Science Key Basic Research of Jiangsu Province for Higher Education (Nos. 06KJA15007, 05KJB150116, 05KJD150251), the Jiangsu Provincial Key Laboratory of Fine Petrochemical Technology (KF0402), the Jiangsu Provincial Key Laboratory of Coastal Wetland Bioresources and Environmental Protection (JLCBE06008), and a research grant from the Innovation Project for Graduate Students of Jiangsu Province. |
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| Keywords: | Chalcone ferrocene Michael addition microwave irradiation solvent-free |
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