Highly Efficient Solvent-Free Synthesis of Dihydropyrimidinones Catalyzed by Zinc Oxide |
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| Authors: | Kiumars Bahrami Mohammad Mehdi Khodaei Azita Farrokhi |
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| Affiliation: | 1. Department of Chemistry , Razi University , Kermanshah, Iran;2. Nanoscience and Nanotechnology Research Center (NNRC) , Razi University , Kermanshah, Iran kbahrami2@hotmail.com;4. Nanoscience and Nanotechnology Research Center (NNRC) , Razi University , Kermanshah, Iran;5. Department of Chemistry , Razi University , Kermanshah, Iran |
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| Abstract: | A simple, efficient and practical procedure for the Biginelli reaction using zinc oxid (ZnO) as a novel and reusable catalyst is described under solvent-free conditions in high yields. The use of this agent is characterized by remarkable reactivity, moderate costs, low toxicity and simple work up procedures. |
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| Keywords: | Cyclocondensation solvent-free 1,2,3,4-tetrahydropyrimidine zinc oxide |
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