Synthesis of 2-Arylquinazolin-4(3H)-one Derivatives Catalyzed by Iodine in [bmim+][ ] |
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| Authors: | Xiang-Shan Wang Ke Yang Mei-Mei Zhang Chang-Sheng Yao |
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| Institution: | 1. School of Chemistry and Chemical Engineering , Xuzhou Normal University , Xuzhou, Jiangsu, China;2. Key Laboratory of Biotechnology on Medical Plants , Xuzhou, Jiangsu, China xswang1974@yahoo.com;4. School of Chemistry and Chemical Engineering , Xuzhou Normal University , Xuzhou, Jiangsu, China;5. Key Laboratory of Biotechnology on Medical Plants , Xuzhou, Jiangsu, China |
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| Abstract: | Controlling selectivity of the reactions of aromatic aldehydes and 2-aminobenzamide in ionic liquid catalyzed by iodine at either room temperature or at 80 °C under nitrogen resulted in the synthesis of (E)-Schiff bases, 2,3-dihydro-2-arylquinazolin-4(1H)-one and 2-arylquinazolin-4(3H)-one derivatives, in excellent yields. |
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| Keywords: | 2-Aminobenzamide iodine ionic liquid quinazolin-4(1H)-one synthesis |
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