An α-Lactam as an Alkilating Agent |
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Authors: | István Langyel Robert V. Mark |
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Affiliation: | Department of Chemistry , St. Jone's University , Jamaica , New York, 11432 |
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Abstract: | The ‘normal’ reaction of α-lactams (aziridinones) is mcleophilic ring ening,1 which can occur with fission of either one of the three bonds (a-b-c), depending on the reagent, to yield and acyclic addition prodnct (I,II,III).2 |
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