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Lactam Coupling as a Versatile Route to Indoprofen Analogs |
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| Authors: | Keith D. Barnes Ping Chen Yingyan Chang Robert M. Lewis Christopher M. Manley Nicholas J. Mayhew |
| Affiliation: | Medicinal Chemistry Department , AMRI , Albany, New York, USA |
| Abstract: | A convergent synthesis of indoprofen via a Buchwald coupling approach is reported. Using this methodology, indoprofen and a set of analogs of indoprofen were readily prepared. |
| Keywords: | Buchwald–Hartwig cross-coupling indoprofen palladium |