Aqueous Synthesis of N-Phenyl/alkyl-2-quinolinone-3-carboxylic Acids from Coumarin-3-carboxylic Acids |
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| Authors: | H. N. Harishkumar Vijay Kumar Hulikal |
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| Affiliation: | 1. Department of Postgraduate Studies and Research in Chemistry , School of Chemical Sciences, Kuvempu University , Shankaraghatta, Karnataka, India;2. Bio-organics and Applied Materials Pvt. Ltd. , Bangalore, India |
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| Abstract: | An efficient, ecofriendly aqueous synthesis of aromatic/aliphatic amines with coumarin-3-carboxylic acid in a one pot reaction in a sealed tube or InCl3/ H2O in open vessel to afford N-phenyl/alkyl-2-quinolinones is achieved. This method provides high yield of products in shorter time, making it a useful process for the synthesis of structurally diversified 2-quinolinones from corresponding coumarins. |
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| Keywords: | Coumarin-3-carboxylic acid N-phenyl/alkyl-2-quinolinones one pot |
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