Facile,Highly Stereoselective Synthesis of Cyclopropyl Benzoimidazoles via Cyclopropanation of Olefin with Arsonium Ylides |
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| Authors: | Weiqi Tong Changqing Wang Wenwen Zhao Jie Chen Xiaoyu Wu Min Zhang |
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| Institution: | Department of Chemistry , Shanghai University , Shanghai, China |
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| Abstract: | A facile and highly stereoselective methodology for the preparation of highly functionalized trans-1,2-cyclopropanes containing benzoimidazolyl, cyano, aryl, and carbonyl groups 3 is described. Arsonium bromides 2 reacted with electron-deficient olefins 1 in the presence of KF·2H2O to provide 3 exclusively with high stereoselectivity in moderate to good yields. |
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| Keywords: | Arsonium ylide cyclopropanes cyclopropyl benzoimidazoles stereoselectivity |
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