InCl3-Promoted Synthesis of Pyrazolyl-Substituted Quinolines in Green Media |
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| Authors: | Gopal Senthil Kumar Werner Kaminsky |
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| Affiliation: | 1. Department of Chemistry, Bharathiar University, Coimbatore, India;2. Department of Chemistry, University of Washington, Seattle, Washington, USA |
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| Abstract: | A series of regioisomers of pyrazolyl-substituted quinolines has been synthesized through the simple condensation reaction between hydrazinylquinolines with aliphatic 1,3-diketones with InCl3 as a catalyst under microwave irradiation. This method produces pure products in good yield in a rapid manner compared to conventional procedures and withneat reaction condition. The approach has the advantages of operational simplicity and increased safety for a shortened synthesis of pyrazolyl-substituted quinolines. |
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| Keywords: | Green synthesis hydrazinylquinolines pyrazolyl-substituted quinolines regioisomers |
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