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New Approach for the Synthesis of N‐Indolyl Ketones and Aldehydes
Authors:Hua‐Sheng Ding  Yu‐Yuan Xie
Institution:1. State Key Laboratory of Drug Research , Shanghai Institute of Materia Medica , Shanghai, China;2. Graduate School of the Chinese Academy of Science , Beijing, China
Abstract:A new approach for the synthesis of N‐indolyl ketones and aldehydes was developed. In the reaction of N‐indolyl carboxylic acids with alkyl lithium, an interesting phenomenon appeared when using THF as solvent instead of ethyl ether.
Keywords:Alkyl lithium  N‐indolyl aldehyde  N‐indolyl ketone  solvent effect
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