Oxidation of Sulfides with Hydrogen Peroxide Catalyzed by Vitamin B2 Derivatives |
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| Authors: | Yasushi Imada Masamitsu Takagishi Naruyoshi Komiya |
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| Institution: | 1. Department of Chemistry, Graduate School of Engineering Science , Osaka University , Machikaneyama, Toyonaka , Osaka , Japan;2. Department of Chemical Science and Technology , Institute of Technology and Science, The University of Tokushima , Minamijosanjima , Tokushima , Japan imada@chem.tokushima-u.ac.jp;4. Department of Chemistry, Graduate School of Engineering Science , Osaka University , Machikaneyama, Toyonaka , Osaka , Japan |
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| Abstract: | 5-Ethyl-3-methyl-2′,4′:3′,5′-di-O-methylenedioxyriboflavinium perchlorate (1, DMRFlEt+ClO4 –), derived readily from commercially available vitamin B2 (riboflavin), exhibits high catalytic activity for the oxidation of organic sulfides with hydrogen peroxide. The reaction provides an efficient and selective method for the oxidative transformation of organic sulfides to the corresponding sulfoxides under mild conditions. Supplementary materials are available for this article. Go to the publisher's online edition of Synthetic Communications® for the following free supplemental resource: Full experimental and spectral details.] |
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| Keywords: | H2O2 oxidation organocatalysis sulfides sulfoxides |
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