Preparation of Isoquinolin-(2(1H)-yl)but-2-enedioate Derivatives |
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| Authors: | Mohammad Anary Abbasinejad Mohammad Hossein Mosslemin Hadi Esfandiari |
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| Institution: | 1. Department of Chemistry , Islamic Azad University–Yazd Branch , Yazd, Iran;2. Department of Chemistry , Islamic Azad University–Neyriz Branch , Neyriz, Iran |
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| Abstract: | One-pot, three-component reactions of isoquinoline, dimethyl/diethyl acetylenedicarboxylate, and indole, carbazole, pyrazole, or imidazole gave dimethyl/diethyl 2-(1-(1H-indol-1-yl)isoquinolin-2(1H)-yl)but-2-enedioate, dimethyl/diethyl 2-(1-(9H-carbazol-9-yl)isoquinolin-2(1H)-yl)but-2-enedioate, dimethyl 2-(1-(1H-pyrazol-1-yl)isoquinolin-2(1H)-yl)but-2-enedioate, or dimethyl 2-(1-(1H-imidazol-1-yl)isoquinolin-2(1H)-yl)but-2-enedioate respectively in good to excellent yields. |
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| Keywords: | Carbazole dialkyl acetylenedicarboxylate indole isoquinolin-2(1H)-yl)but-2-enedioate isoquinoline |
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