Convenient Ultrasound-Promoted Regioselective Synthesis of Fused 6-Amino-3-methyl-4-aryl-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile |
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| Authors: | Leila Zare Asieh Yahyazadeh Manouchehr Mamaghani |
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| Affiliation: | Department of Chemistry , Faculty of Sciences, University of Guilan , Rasht , Iran |
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| Abstract: | A multicomponent, catalyst-free reaction for the synthesis of fused 6-amino-3-methyl-4-aryl-1H-pyrazolo [3,4-b] pyridine-5-carbonitrile from 3-amino-5-methylpyrazole, malononitrile, and substituted aldehydes under ultrasound irradiation in short reaction times (8–10 min) with good yields (85–98%) is reported.  Additional information ACKNOWLEDGMENT We thank the Research Committee of University of Guilan for the partial support given to this study. |
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| Keywords: | 3-Amino-5-methylpyrazole fused 6-amino-3-methyl-4-aryl-1H-pyrazolo [3,4-b] pyridine-5-carbonitrile malononitrile multicomponent |
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