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Convenient Synthesis of 3,5‐Disubstituted Isoxazoles
Authors:Reshma F. Kurangi  Rima Kawthankar  Sulfala Sawal  Santosh G. Tilve
Affiliation:1. Department of Chemistry , Goa University , Goa, India;2. Department of Chemistry , Dnyanprassarak Mandal's College of Arts, Science, and Commerce , Assagao, Mapusa, Bardez, Goa, India
Abstract:α,β‐Unsaturated oximes obtained from the corresponding α,β‐unsaturated ketones on treatment with 2 equivalents of manganese dioxide in refluxing chloroform gives 3,5‐disubstituted isoxazoles in good yields.
Keywords:heterocycle  isoxazole  MnO2  oxidative cyclisation
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