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Simple Synthesis of Deuterated Pterosines
Authors:Gaetano Miele  Roberta Costi  Francesco Bonadies  Rosario Nicoletti
Affiliation:1. Department of Pharmaceutical Studies , “Sapienza” University of Rome , Rome, Italy gaetano.miele@uniroma1.it;3. Department of Pharmaceutical Studies , “Sapienza” University of Rome , Rome, Italy;4. Department of Chemistry , “Sapienza” University of Rome , Rome, Italy
Abstract:Ptaquiloside, a potent carcinogen present in bracken fern, a plant consumed by farm animals, may be detected in traces by converting it into the bromopterosine. A simple synthesis of bromopterosine d2, to be used as standard in GC/MS or LC/MS analyses, is described.
Keywords:Deuterated compounds  pterosines  ptaquiloside  sesquiterpene glucoside
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