Highly Efficient Michael Addition Reaction of Amines Catalyzed by Silica-Supported Aluminum Chloride |
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Authors: | Mohammad R Saidi Yaghoub Pourshojaei Fezzeh Aryanasab |
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Institution: | 1. Department of Chemistry , Sharif University of Technology , Tehran, Iran saidi@sharif.edu;3. Department of Chemistry , Sharif University of Technology , Tehran, Iran |
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Abstract: | Aliphatic and aromatic amines undergo smooth nucleophilic addition to α,β-unsaturated compounds in the presence of a catalytic amount of silica-supported aluminum chloride at 60 °C and under solvent-free conditions to produce the corresponding β-amino compounds in excellent yields. This method is simple and convenient and works efficiently under mild conditions. This catalyst can used again without losing its activity three times. |
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Keywords: | Amines Michael addition silica-supported aluminum chloride α" target="_blank">α β-unsaturated olefins" target="_blank">β-unsaturated olefins |
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