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Rearrangement of Ethers: A New Route to Tolterodine
Authors:Veera Reddy Arava  Sreenivasula Reddy Bandatmakuru  Sashibhushan Malreddy  Narayanaswamy Golla
Affiliation:1. Research Development Centre, Suven Life Sciences Ltd. , Hyderabad , India reddyvenis@rediffmail.com;3. Research Development Centre, Suven Life Sciences Ltd. , Hyderabad , India;4. Department of Chemistry , Sri Krishnadevaraya University , Anantapur , India
Abstract:Efficient methods for the syntheses of amines 6b and 9b, the major metabolites of the antidepressant drugs amitriptyline 1a and nortriptyline 1b, are described.
Keywords:Aluminum chloride  perchloric acid  rearrangement
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