Facile Method for One-Step Synthesis of 2,4,5-Triarylimidazoles Under Catalyst-Free,Solvent-Free,and Microwave-Irradiation Conditions |
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Authors: | Jian-Feng Zhou Gui-Xia Gong Xiao-Jun Sun Yu-Lan Zhu |
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Affiliation: | 1. Department of Chemistry , Huaiyin Teachers College, Jiangsu Key Laboratory for Chemistry of Low-Dimensional Materials , Huaian, China;2. School of Chemistry and Chemical Engineering, Key Laboratory of Organic Synthesis of Jiangsu Province, Suzhou University , Suzhou, China orgjfzhou@yahoo.com.cn;4. School of Chemistry and Chemical Engineering, Key Laboratory of Organic Synthesis of Jiangsu Province, Suzhou University , Suzhou, China;5. Department of Chemistry , Huaiyin Teachers College, Jiangsu Key Laboratory for Chemistry of Low-Dimensional Materials , Huaian, China |
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Abstract: | A green and efficient method for the synthesis of 2,4,5-triarylimidazoles by one-step condensation reaction of benzil, aromatic aldehyde, and ammonium acetate under catalyst-free, solvent-free, and microwave-irradiation conditions is reported. This method had many dramatic advantages, such as the short reaction time (3–5 min), good yields (80–99%), environmental friendliness, and convenient operation. |
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Keywords: | Aromatic aldehyde benzil catalyst-free microwave irradiation solvent-free triarylimidazole |
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