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Preparation and Optical Properties of Novel 3-Alkoxycarbonyl Aza- and Diazacoumarins
Authors:Clémentine Féau  Emmanuel Klein  Paul Kerth
Affiliation:1. Laboratoire de Chimie Organique Appliquée, CAMB, CNRS–UdS, Faculté de Pharmacie , Illkirch, France;2. Preventor μTBC GmbH , Pfungstadt, Germany
Abstract:A series of 14 new 3-alkoxycarbonyl 6-aza-, 7-aza-, and 6,8-diaza-coumarins was prepared using various strategies involving either a Knoevenagel or a Pechmann condensation reaction. The coumarin nucleus displays different reactive functional groups allowing straightforward derivatization. The optical properties of the new azacoumarins were measured in methanol.
Keywords:Azacoumarin  chromophore  coumarin  Knoevenagel condensation  Pechmann condensation
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