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A Facile and Efficient Synthesis of 3-Aryloxazolidin-2-ones from Isocyanates and Epoxides Promoted by MgI2 Etherate |
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| Authors: | Xingxian Zhang Wei Chen Chengfeng Zhao Cheng Li Xiang Wu Wei Z Chen |
| Institution: | 1. College of Pharmaceutical Sciences, Zhejiang University of Technology , Hangzhou, Zhejiang, P. R. China zhangxx@zjut.edu.cn;3. College of Pharmaceutical Sciences, Zhejiang University of Technology , Hangzhou, Zhejiang, P. R. China |
| Abstract: | We described a mild and efficient procedure for the synthesis of 3-aryloxazolidin-2-ones via the cycloaddition of isocyanates with epoxides in the presence of MgI2 etherate (MgI2 ? (OEt2)n) in good yields. |
| Keywords: | Epoxide isocyanate MgI2 etherate oxazolidinone |