Metal-Free Direct Hydrosulfonylation of Azodicarboxylates with Sulfinic Acids Leading to Sulfonylhydrazine Derivatives |
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| Authors: | Jiangwei Wen Daoshan Yang Yufeng Fan Lulu Fu |
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| Affiliation: | Key Laboratory of Life Organic Analysis and Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu, Shandong, China |
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| Abstract: | A metal-free direct hydrosulfonylation protocol of azodicarboxylates with sulfinic acids has been developed for the construction of sulfonylhydrazine-1,2-dicarboxylates at room temperature. This methodology provides an efficient and practical approach to prepare various sulfonylhydrazine-1,2-dicarboxylates in good to excellent yields, which has the advantages of operation simplicity, environmental friendliness, high atom economy, and mild reaction conditions. |
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| Keywords: | Hydrosulfonylation metal-free sulfinic acids sulfonylhydrazine-1,2-dicarboxylates |
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