AlCl3 as an Effective Lewis Acid for the Synthesis of Arylaminotetrazoles |
| |
| Authors: | Davood Habibi Mahmoud Nasrollahzadeh Yadollah Bayat |
| |
| Institution: | 1. Department of Organic Chemistry , Bu-Ali Sina University , Hamedan , Iran davood.habibi@gmail.com;3. Department of Organic Chemistry , Bu-Ali Sina University , Hamedan , Iran;4. Department of Chemistry , Malek-Ashtar University of Technology , Tehran , Iran |
| |
| Abstract: | An efficient method for preparation of the arylaminotetrazoles derivatives is reported using aluminium chloride as an effective Lewis acid. Generally, 5-arylamino-1H-tetrazole isomer can be obtained from arylcyanamides carrying electron-withdrawing substituents on the aryl ring. As the electropositivity of the substituent is increased, the product is shifted toward the formation of 1-aryl-5-amino-1H-tetrazole isomer. |
| |
| Keywords: | AlCl3 5-arylamino-1H-tetrazole 1-aryl-5-amino-1H-tetrazole arylcyanamide Lewis acid |
|
|
