Synthesis and Characterization of Benzenesulfonyl Hydrazones and Benzenesulfonamides |
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Authors: | Kely Navakoski de Oliveira |
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Institution: | Chemistry Department , Universidade Federal de Santa Catarina , Florianópolis, Santa Catarina, Brazil |
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Abstract: | In the search for structural cyclic imide analogues of therapeutic interest, the syntheses and characterization of benzenesulfonyl hydrazones and benzenesulfonamides are described. The benzenesulfonyl chlorides (2) and (3) were obtained through the Diels–Alder reaction between N‐p‐chloro‐sulfonylfenylmaleimide (1) and furan or 2‐methylfuran. The reactions of (2) and (3) with hydrazine and amines afforded the hydrazides and sulfonamides, respectively. The sulfonylhydrazones were obtained through a condensation between the sulfonylhydrazides with different benzaldehydes. |
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Keywords: | Benzenesulfonyl chlorides Diels–Alder reaction sulfonamides sulfonylhydrazones |
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