Efficient One-Pot Synthesis of Polyhydroquinoline Derivatives Using Silica Sulfuric Acid as a Heterogeneous and Reusable Catalyst Under Conventional Heating and Energy-Saving Microwave Irradiation |
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Authors: | Akbar Mobinikhaledi Naser Foroughifar Mohammad Ali Bodaghi Fard Hassan Moghanian Sattar Ebrahimi Mehdi Kalhor |
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Institution: | 1. Department of Chemistry , Faculty of Sciences, Arak University , Arak, Iran akbar_mobini@yahoo.com;3. Department of Chemistry , Faculty of Sciences, Arak University , Arak, Iran |
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Abstract: | An efficient Hantzsch four-component condensation reaction for the synthesis of polyhydroquinoline derivatives was reported under two conditions: solvent-free conventional heating and energy-saving microwave irradiation. The process is simple and environmentally benign, and the use of a heterogeneous and reusable catalyst, high yields, and short reaction times are the key features of this protocol. |
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Keywords: | Heterogeneous polyhydroquinoline silica sulfuric acid |
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