Direct Reductive Amination of Aldehydes and Ketones with 2,4-Ionene-Based Borohydride Exchange Resin as a Novel Polymer-Supported Reducing Agent |
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| Authors: | Mahmood Tajbakhsh Moslem Mansour Lakouraj Majid Shabani Mahalli |
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| Affiliation: | 1. Department of Chemistry , Faculty of Basic Science, Mazandaran University , Babolsar, Iran Tajbaksh@umz.ac.ir;3. Department of Chemistry , Faculty of Basic Science, Mazandaran University , Babolsar, Iran |
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| Abstract: | Direct reductive amination of aldehydes and ketones were accomplished efficiently using high-capacity, ionene-based, polymer-supported borohydride reagent in isopropyl alcohol at reflux under neutral conditions. The reagent is easily prepared by mixing aqueous solution of 2,4-ionene bromide with an alkaline solution of sodium borohydride at room temperature. The generality of reaction was established using both aliphatic and aromatic aldehydes, ketones, and amines. |
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| Keywords: | 2,4-ionene Aldehydes Borohydride exchange resin Ketones Reductive amination |
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