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2-phenyl thiazolidine — its growth and characterisation
Authors:R Umarani  S Eswaramoorthy  K S Raju
Abstract:The importance of 2-phenyl thiazolidine lies in its being a model for penicillin, as the five-membered thiazolidine ring happens to be the moiety of penicillin. This material is synthesised and crystallised (Tsukerman). The crystals are white in colour, transparent, needle-shaped and of dimensions (0.2 × 0.3 × 0.4 mm3). Employing X-ray diffraction studies, it is found that the crystal belongs to the orthorhombic system with the unit cell parameters a = 8.388(1), b = 18.114(2) and c = 5.625(1) Å. The space group is P 212121 and Z = 4. The absorption peaks pertaining to NH, NCS, methylene CH2 and aromatic C6H4 have been identified from the infrared absorption spectrum of the sample. The Proton Magnetic Resonance (PMR) spectrum fully accounts for the hydrogens in the sample thereby unambigiously supporting the proposed structure.
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