Synthesis of indenoindene-fused α-methylene-γ-butyrolactones via a tandem intra- and intermolecular Friedel-Crafts reaction |
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| Authors: | Bo Ram ParkSe Hee Kim Yu Mi KimJae Nyoung Kim |
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| Institution: | Department of Chemistry and Institute of Basic Science, Chonnam National University, Gwangju 500-757, Republic of Korea |
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| Abstract: | An efficient synthesis of indenoindene-fused α-methylene-γ-butyrolactones was carried out via a tandem intra- and intermolecular Friedel-Crafts reaction from the spiro-lactone, which can be easily prepared from ninhydrin by indium-mediated Barbier reaction of cinnamyl bromide. |
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| Keywords: | α-Methylene-γ-butyrolactone Indenoindene Friedel-Crafts reaction |
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