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SYNTHESIS OF DERIVATIVES OF 3-β-D-XYLOPYRANOSYL-1,2,4-OXADIAZOLES
作者姓名:Ling Jiao DONG  Li LI  Ling Tai MA  Li He ZHANG
作者单位:School of Pharmaceutical Sciences, Beijing Medical University, Beijing 100083
摘    要:The synthesis of derivatives of 3-β-D-xylopyranosyl-1,2,4-oxadiazolesis accomplished by condensing protected β-D-xylopyranosyl amidoxime with acidanhydrides or various substituted benzoyl chlorides in good yield.Thestructures of now derivatives were identified by spectra and elemental analysis.The stability of 1,2,4-oxadiazole ring and mechanism of cyclization were.investigated.


SYNTHESIS OF DERIVATIVES OF 3-β-D-XYLOPYRANOSYL-1,2,4-OXADIAZOLES
Ling Jiao DONG,Li LI,Ling Tai MA,Li He ZHANG.SYNTHESIS OF DERIVATIVES OF 3-β-D-XYLOPYRANOSYL-1,2,4-OXADIAZOLES[J].Chinese Chemical Letters,1992,3(8):597-600.
Authors:Ling Jiao DONG  Li LI  Ling Tai MA  Li He ZHANG
Institution:School of Pharmaceutical Sciences, Beijing Medical University, Beijing 100083
Abstract:The synthesis of derivatives of 3-β-D-xylopyranosyl-1,2,4-oxadiazoles is accomplished by condensing protected β-D-xylopyranosyl amidoxime with acid anhydrides or various substituted benzoyl chlorides in good yield.The structures of now derivatives were identified by spectra and elemental analysis. The stability of 1,2,4-oxadiazole ring and mechanism of cyclization were investigated.
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