| 新型含苯并噻唑基双酰胺衍生物的合成及其抗菌活性 |
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| 引用本文： | 薛伟,熊壮,郑玉国,何勇,魏学,祁慧雪,卢平.新型含苯并噻唑基双酰胺衍生物的合成及其抗菌活性[J].合成化学,2012,20(4):411-415,447. |
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| 作者姓名： | 薛伟 熊壮 郑玉国 何勇 魏学 祁慧雪 卢平 |
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| 作者单位： | 1. 贵州大学精细化工研究开发中心教育部绿色农药与农业生物工程重点实验室,贵州贵阳,550025
2. 贵州大学精细化工研究开发中心教育部绿色农药与农业生物工程重点实验室,贵州贵阳550025;兴义民族师范学院化学生物系,贵州兴义562400 |
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| 基金项目： | 国家自然科学基金资助项目，贵州大学人才基金资助项目 |
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| 摘 要： | 以邻甲基苯甲酸和取代邻氨基苯甲酸为起始原料,设计并合成了10个未见文献报道的含苯并噻唑基双酰胺类衍生物,其结构经1H NMR,13C NMR,IR及元素分析表征。初步的抗菌活性测试结果表明,在500 mg.L-1浓度下部分化合物对黄瓜花叶病毒(CMV)有一定抑制作用。
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| 关 键 词： | 双酰胺 苯并噻唑 合成 抗菌活性 |
Synthesis and Antibacterial Activities of Novel Bisamides Derivatives Containing Benzothiazole |
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| XUE Wei
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XIONG Zhuang
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ZHENG Yu-guo
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HE Yong
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WEI Xue
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QI Hui-xue
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LU Ping.Synthesis and Antibacterial Activities of Novel Bisamides Derivatives Containing Benzothiazole[J].Chinese Journal of Synthetic Chemistry,2012,20(4):411-415,447. |
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| Authors: | XUE Wei XIONG Zhuang ZHENG Yu-guo HE Yong WEI Xue QI Hui-xue LU Ping |
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| Institution: | 1(1.Key Laboratory of Green Pesticide and Bioengineering,Ministry of Educational, Research and Development Center for Fine Chemicals,Guizhou University,Guiyang 550025,China; 2.Department of Chemistry and Biological,Xingyi Normal College,Xingyi 562400,China) |
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| Abstract: | Ten novel bisamides derivatives containing benzothiazole were designed and synthesized from o-methylbenzoic acid and substituted-o-aminobenzoic acid.The structures were characterized by 1H NMR,13C NMR,IR and elemental analysis.The preliminary antibacterial activities tests showed that some of them exhibited certain antiviral activities against CMV. |
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| Keywords: | bisamides benzothiazole synthesis antibacterial activity |
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