| 一种腙水解合成醛(酮)的绿色化学方法 |
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| 引用本文： | 全娜,董菁,吕霞,聂良邓,朱瑞恒,施小新.一种腙水解合成醛(酮)的绿色化学方法[J].合成化学,2012,20(3):363-365. |
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| 作者姓名： | 全娜 董菁 吕霞 聂良邓 朱瑞恒 施小新 |
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| 作者单位： | 华东理工大学药学院制药工程系,上海,200237 |
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| 基金项目： | 国家自然科学基金资助项目，上海市教育发展基金资助项目 |
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| 摘 要： | 腙与二水合氯化铜在80%乙腈溶液中回流反应1 h～3 h,高收率地制得相应的醛(酮)。实现了铜盐的循环使用,符合绿色化学理念。
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| 关 键 词： | 腙 二水合氯化铜 水解 绿色化学 合成 |
A Green Method for Synthesis of Carbonyl Compounds by Hydrolysis of Hydrazones |
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| QUAN Na
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DONG Jing
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LV Xia
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NIE Liang-deng
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ZHU Rui-heng
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SHI Xiao-xin.A Green Method for Synthesis of Carbonyl Compounds by Hydrolysis of Hydrazones[J].Chinese Journal of Synthetic Chemistry,2012,20(3):363-365. |
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| Authors: | QUAN Na DONG Jing LV Xia NIE Liang-deng ZHU Rui-heng SHI Xiao-xin |
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| Institution: | (Department of Pharmaceutical Engineering,School of Pharmacy, East China University of Science and Technology,Shanghai 200237,China) |
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| Abstract: | Carbonyl compounds in high yields were synthesized by hydrolysis of hydrazones with cupric chloride dihydrate(CuCl2·2H2O,2 eq.) in 80% acetonitrile aqueous under reflux.In addition,cupric salt was readily recovered in an almost quantitative yield via the complete precipitation of Cu(OH)2,which could be reused for the above hydrolysis of hydrazones after being converted into CuCl2·2H2O. |
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| Keywords: | hydrazones hydrolysis cupric chloride dihydrate green chemistry synthesis |
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