A new analytical device incorporating a nitrogen doped lanthanum metal oxide with reduced graphene oxide sheets for paracetamol sensing

The novel N-CeO₂ nanoparticles decorated on reduced graphene oxide (N-CeO₂@rGO) composite has been synthesized by sonochemical method. The characterization of as prepared nanocomposite was intensely performed by UV–Vis, FT-IR, EDX, FE-SEM, HR-TEM, XRD, and TGA analysis. The synthesized nanomaterial was further investigated for its selective and sensitive sensing of paracetamol (PM) based on a N-CeO₂@rGO modified glassy carbon electrode. A distinct and improved reversible redox peak of PM is obtained at N-CeO₂@rGO nanocomposite compared to the electrodes modified with N-CeO₂ and rGO. It displays a very good performance with a wide linear range of 0.05–0.600 μM, a very low detection limit of 0.0098 μM (S/N = 3), a high sensitivity of 268 μA µM⁻¹ cm⁻² and short response time (<3 s). Also, the fabricated sensor shows a good sensibleness for the detection of PM in various tablet samples.