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A convenient synthesis of cis and trans 4-tert-butoxycarbonyl-substituted cyclohexylglycine |
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| Authors: | Venkatraman Srikanth Njoroge F George Girijavallabhan Viyyoor McPhail Andrew T |
| Affiliation: | Schering Plough Research Institute, A301, K-15, mailstop 3545, 2015 Galloping Hill Road, Kenilworth, NJ 07033, USA. Srikanth.Venkatraman@spcorp.com |
| Abstract: | A novel synthesis of cis and trans substituted 4-tert-butoxycarbonyl cyclohexylglycines via asymmetric aminohydroxylation of vinyl styrene followed by reduction of the aromatic ring and subsequent oxidation is reported. |
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