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BioMOFs: Metal–Organic Frameworks for Biological and Medical Applications |
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| Authors: | Alistair?C McKinlay Russell?E Morris Prof Patricia Horcajada Dr Gérard Férey Prof Ruxandra Gref Dr Patrick Couvreur Prof Christian Serre Dr |
| Institution: | 1. EaStChem School of Chemistry, University of St Andrews, Purdie Building, St Andrews, KY16 9ST (UK), Fax: (+44)?1334‐463‐808;2. Institut Lavoisier, UMR CNRS 8180, Universite de Versailles St Quentin en Yvelines, 45 avenue des Etats‐Unis, 78035 Versailles (France), Fax: (+33)?1‐3925‐4452;3. Faculté de Pharmacie (CNRS 8612), Université Paris‐Sud, 92296 Chatenay‐Malabry (France), 3CNRS 2301, 91190 Gif‐sur‐Yvette (France) and CNRS8081, Université PARIS‐Sud 91405 Orsay (France) |
| Abstract: | The class of highly porous materials called metal–organic frameworks offer many opportunities for applications across biology and medicine. Their wide range of chemical composition makes toxicologically acceptable formulation possible, and their high level of functionality enables possible applications as imaging agents and as delivery vehicles for therapeutic agents. The challenges in the area encompass not only the development of new solids but also improvements in the formulation and processing of the materials, including tailoring the morphology and surface chemistry of the frameworks to fit the proposed applications. |
| Keywords: | drug delivery metal– organic frameworks nitric oxide theranostics |