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Applications of capillary electrophoresis with capacitively coupled contactless conductivity detection (CE‐C4D) in pharmaceutical and biological analysis
Authors:Abdalla A Elbashir  Hassan Y Aboul‐Enein
Institution:1. Faculty of Science, Chemistry Department, University of Khartoum, P.O. Box 321, Khartoum, Sudan;2. Pharmaceutical and Medicinal Chemistry Department, National Research Centre, Dokki, Cairo 12311, Egypt;3. Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia
Abstract:Conductivity detection, which is universal in capillary electrophoresis (CE), has received considerable attention, since the introduction of the axial capacitively coupled contactless detector C4D in 1998. This detector is made of two electrodes which are placed cylindrically around the CE capillary and connected to the AC oscillator. The distance between the electrodes is the detection gap. In this review, applications of CE and MCE with C4D in pharmaceutical and biological analysis are presented.
Keywords:capillary electrophoresis  capacitively coupled contactless conducuctivity  pharmaceutical analysis  biological analysis
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