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A Scaffold‐Tree‐Merging Strategy for Prospective Bioactivity Annotation of γ‐Pyrones
Authors:Samy Chammaa Dr  Bianca Sperl  Anke?G Roth  Aybike Yektaoglu  Steffen Renner Dr  Thorsten Berg Prof?Dr  Christoph Arenz Prof?Dr  Athanassios Giannis Prof?Dr  Tudor?I Oprea Dr  Daniel Rauh Dr  Markus Kaiser Dr  Herbert Waldmann Prof?Dr
Institution:1. Department of Chemical Biology, Max Planck Institute of Molecular Physiology, Otto‐Hahn‐Strasse 11, 44227 Dortmund (Germany);2. Faculty of Chemistry, Chemical Biology, Technical University Dortmund, Dortmund (Germany);3. Department of Molecular Biology, Max Planck Institute of Biochemistry and Center for Integrated Protein Science Munich (CIPSM), Am Klopferspitz 18, 82152 Martinsried (Germany);4. Institut für Chemie, Humboldt‐Universit?t zu Berlin, Brook‐Taylor‐Strasse 2, 12489 Berlin (Germany);5. Institute of Organic Chemistry, University of Leipzig, Johannisallee 29, 04103 Leipzig (Germany);6. Present address: Novartis Institutes of Biomedical Research, Basel (Switzerland);7. New address: Institute of Organic Chemistry, University of Leipzig (Germany);8. Division of Biocomputing, University of New Mexico School of Medicine, Albuquerque, NM 87131 (USA);9. Chemical Genomics Centre of the Max Planck Society, Otto‐Hahn‐Strasse 15, 44227 Dortmund (Germany)
Abstract:
Keywords:chemical space  cheminformatics  natural products  scaffold trees  target space
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