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Induced‐Fit Binding of the Macrocyclic Noncovalent Inhibitor TMC435 to its HCV NS3/NS4A Protease Target |
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| Authors: | Maxwell D Cummings Jimmy Lindberg Tse‐I Lin Herman de Kock Oliver Lenz Elisabet Lilja Sara Felländer Vera Baraznenok Susanne Nyström Magnus Nilsson Lotta Vrang Michael Edlund Åsa Rosenquist Bertil Samuelsson Pierre Raboisson Kenneth Simmen |
| Institution: | 1. Tibotec BVBA, Gen De Wittelaan L 11B 3, 2800 Mechelen (Belgium), Fax: (+32)?15‐286‐374;2. Medivir AB, Lunastigen 7, 14144 Huddinge (Sweden) |
| Abstract: | |
| Keywords: | drug design hepatitis C inhibitors protein structures |